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painkillers are unsuitable for 6 kinds of people

Clinical research found that 46% - 75% of those who use nsaids in long terms have appeared stomach bleeding or ulcer. Each year in the United States the hospitalized patients with this reason are more than 100000. To avoid this kind of gastric mucosa damage, you should know yourself well before using the drugs.

1. The elderly
Experts say, compared with the young ones, the body defense ability of the elderly will drop. The mucous membrane defense function will decline and the risk of stomach bleeding and perforation increase 13.2 times. Therefore, if you want to take nsaids, it is better to choose the medicine which has smaller gastrointestinal side effects, such as celecoxib.
2. Those who have stomach troubles
If people with stomach problems take nsaids, it will definitely make the condition worse. Studies have shown that patients with gastrointestinal diseases will have 2.4 times higher risk of gastrointestinal hemorrhage after taking non-steroidal anti-inflammatory drug for one time in 150 days and 7.4 times higher risk if taking for several times.

3. Those who take anticoagulants.
Anticoagulant is widely used for the prevention and control of diseases like dynamic and venous thromboembolism. Studies have shown that ibuprofen can affect the resistance to the platelet aggregation of aspirin and clopidogrel. Using of non-steroidal anti-inflammatory drug after anticoagulants will cause 12.7 times higher risk of stomach bleeding, after small doses of asprin it will be 7.7 times.
4. Those who take hormone drugs.
Glucocorticoid hormone drugs will be used in diseases from rheumatoid diseases and autoimmune diseases like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis to allergy diseases like allergic rhinitis, eczema and asthma. The risk of peptic ulcer after single use of nsaids will increase 3.8 times, after single use of glucocorticoid hormone 2.6 times, after taking both 9 times.

5. Alcoholics
Long-term drinking will hurt the stomach. A lot of people will take non-steroidal anti-inflammatory drugs after abdominal pain or abdominal distension. Research shows that compared with the alcoholics who don’t take ibuprofen, the risk of gastrointestinal bleeding is 2.7 times higher for those who often take ibuprofen and 1.2 times higher for those who take it occasionally.

6. Smokers
Smoking alone will lead to 1.9 times higher risk of the digestive tract ulcer 1.9 times. If non-steroidal anti-inflammatory drugs has been taken at the same time, the risk will be 4 times higher.

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